High Resolution Microtomography Applications In The Study Of Materials In Restorative Dentistry M. Frascaria*, M. Baldi, M. Giannoni, E. Buelens** (Univ. Studi L’Aquila, Dip. Scienze Chirurgiche, Clinica Odontostom.: Dir. Prof. M. Giannoni** SkyScan, Belgium) The aim of this work is the study “in vitro” of the internal microstructure and behaviour of the composite materials for adhesive restoration at the level of the interface with the different dental tissue (enamel, dentine, cementum).The research has been performed on a sample of 20 extracted human teeth on which have been made cavity preparings and next restorations using composite materials and adhesive systems of the last generation. The microstructural internal caratheristics of the samples have been studied and analyzed using a new compact system desktop of microtomography with high resolution x-ray, “Sky Scan 1072”, which is able to produce images in 3d microscopy non destructive, that gives the great advantage to be able to observe the samples in their natural conditions, without the necessity of performing on them any preparings, suchas, cuts or sections.   So this system represents a new and revolutionary tool of 3d microscopy suitable for the study of the internal microstructure of hard opaque objects (stones, fossils, composites, ceramics, metals, bones, hard and soft tissues, etc..) only recently disposable on market, able to reach a spatial 3d resolution of about 8micron and to point out structural particulars of 3 micron. The results of the research put on evidence the potentialities of this new tool of survey and underline the possibility to study, also in dentistry, the caractheristics and the behaviour of the different kind of restorative materials in relation with the biological tissues.